Dr. Andrew Resnick

Dr. Andrew Resnick
Professor
Location: SI 121
Phone: (216) 687-2437
Fax: (216) 523-7268

My research activity has two main tracks: the role of sensory cilia in cellular mechanosensation and optical probes of matter.  Experimental tools we use include epithelial cell culture and electrophysiology, microscopy and laser tweezers, microfluidics and analytical modeling. Biological systems under investigation include renal and airway epithelial tissue to study the connection between fluid flow stimulation and physiological responses in the context of tissue maintenance and repair.  The nature of our work is highly multidisciplinary, reflecting an idea I believe to be true- important research of the future will be multidisciplinary, and if our results are to contribute meaningfully at the forefront of knowledge, we must be able to cross bridges between disciplines. One of our long term research goals is to bridge the gap between Physics and Biology in the hope that revolutionary new results will be produced.  

Pinak Deshpande
Graduate researcher
Location: SI-142


Ishan Chawan
Doctoral student

N. Zekaj, S. D. Ryan, and A. Resnick, 2023 鈥淔luid-structure interaction modelling of neighboring tubes with primary cilium analysis鈥, Math Biosci Eng. Jan;20(2):3677-3699. doi: 10.3934/mbe.2023172.

Mostafazadeh, N., Resnick, A., Young, Y-N, and Peng, Z., 鈥淢icrostructure-Based Modeling of Primary Cilia Mechanics鈥, submitted to Biophysical Journal, July 2023

Merk, A. and Resnick, A., 2021. Physics of martial arts: Incorporation of angular momentum to model body motion and strikes. Plos one, 16(8), p.e0255670.

Bickel, J., Ellis, A., and Resnick, A. 鈥淓xamining the temperature dependence of louche formation in Absinthe鈥, ACS Omega (2021) DOI: 10.1021/acsomega.1c02246

Peng, Z., Resnick, A. and Young, Y-N. 鈥淧rimary cilium: a paradigm for integrating mathematical modeling with experiments and numerical simulations in mechanobiology鈥 Mathematical Biosciences and Engineering 18(2): 1215-1237 (2021) DOI: 10.3934/mbe.2021066

Van Sickle, J., Schuler, K., Holcomb, J. P., Carver. S., Resnick, A., Quinn, C., Jackson, D., Duffy, S., Sridhar, N. (2020). Closing the Achievement Gap for Underrepresented Minority Students in STEM. Journal of STEM Education: Innovations and Research: 21 (2), 5-18.

Niksa Praljak, Shawn Ryan, and Andrew Resnick, "Pulsatile Flow Through Idealized Renal Tubules: Fluid-Structure Interaction and Dynamic Pathologies", Mathematical Biosciences and Engineering, 17(2) 1787-1807 (2020).

Justin Flaherty, Zhe Feng, Zhangli Peng, Yuan-Nan Young, and Andrew Resnick, 鈥淧rimary cilia have a length-dependent persistence length鈥, Biomech Model Mechanobiol (2019). https://doi.org/10.1007/s10237-019-01220-7

Candice M. Quinn, Derek K. Smith, Michaele F. Chappell, Susan D. Carver, Stephen Duffy, John P. Holcomb, Jr., Debbie Jackson, Andrew Resnick. 鈥淢usic as Math Waves: Exploring Trigonometry through Sound鈥, Journal of Mathematics and the Arts (JMA), Article ID: JMA 1552822 

Nag, S. and Resnick, A. (2017) 鈥淪tabilization of Hypoxia Inducible Factor by Cobalt Chloride Can Alter Renal Epithelial Transport鈥 Physiol Rep, 5 (24), 2017, e13531, 

Susan Carver, Jenna Van Sickle, John P. Holcomb, Candice Quinn, Debbie K Jackson, Andrew H Resnick, Stephen F Duffy, Nigamanth Sridhar, Antoinette M Marquard. 鈥淥peration STEM: increasing success and improving retention among first-generation and underrepresented minority students in STEM鈥, J. STEM Edu. 18 (3) 2017

Nag, S. and Resnick, A. 鈥淏iophysics and Biofluiddynamics of Primary Cilia鈥 (INVITED REVIEW); American Journal of Physiology - Renal Physiology Jun 2017, ajprenal.00172.2017; DOI: 10.1152/ajprenal.00172.2017

Resnick, A 鈥淗IF stabilization weakens primary cilia鈥 PLoS ONE,   Nov. 3, 2016,   

Resnick A. (2015) Mechanical Properties of a Primary Cilium As Measured by Resonant Oscillation. Biophys. J. 109, 1-8 
 
Lofgren, I and Resnick, A. (2015) A Simplified Model for the Optical Force exerted on a Vertically Oriented Cilium by an Optical Trap and the Resulting Deformation. Photonics 2, 604-618; doi:10.3390/photonics2020604 (invited paper).
 
Glaser, J., Hoeprich, D. and Resnick A. (2014) Near real-time measurement of forces applied by an optical trap to a rigid cylindrical object. Opt. Eng., 53 (7), 074110 doi:10.1117/1.OE.53.7.074110.
 
Boslett, B., Nag, S. and Resnick, A. (2014) Detection and Antibiotic Treatment of Mycoplasma arginini Contamination in a Mouse Epithelial cell line Restores Normal Cell Physiology. BioMed Research International 2014, 532105.
 
Resnick A. (2011) Chronic Fluid Flow is an Environmental Modifier of Renal Epithelial Function.  PLoS ONE  6(10): e27058. 
 
Resnick A. (2010) Use of optical tweezers to probe epithelial mechanosensation.  J. Biomedical Optics 15 (1), 015005, 1-8.
 
Yu Cheng, Anna C. Samia,  Jun Li, Ping Zhang, Malcolm E. Kenney, Andy Resnick,Clemens Burda (2010) Quantification the Release of a Gold Nanoparticle-Caged PDT Drug Pc 4 into Human Cancer Cells. Langmuir 26 (4), 2248-2255 (featured article).
 
Resnick A, Hopfer U. (2008) Mechanical stimulation of primary cilia. Frontiers in Bioscience, 13, 1665-1680.
 
Resnick A, Hopfer U. (2007) Force-response considerations in ciliary mechanosensation. Biophys J. 93 (4), 1380-1390.
 
Resnick A (2003) Use of laser tweezers for colloid science. J. Colloid and Interface Science 262, 55-59.
 
Resnick A. (2002) Differential interference contrast microscopy as a polarimetric instrument. Applied Optics 41, 38-45.
 
Resnick A. (2001) Design and Construction of a space-borne optical tweezer apparatus. Review of Scientific Instruments 72, 4059-4065.
 
Resnick A, Persons C., and Lindquist G. (1999) Polarized Emissivity and Kirchhoff鈥檚 Law. Applied Optics 38, 1384-1387.
 
Watson J., Wellfare M., Foster J., Owens M., Vechinski D., Richards M., and Resnick A. (1998) Irma Multisensor Predictive Signature Model. Proc. SPIE Vol. 3375, p. 78-92, Targets and Backgrounds: Characterization and Representation IV, Wendell R. Watkins; Dieter Clement; Eds.
 
Resnick A and Alexander J.I.D., (1997) A Coherent Fourier Optical Imaging System for Liquid Bridge Research. Proc. SPIE Aerosense 1997 meeting, Vol 3073.
 
Resnick A. and Alexander J.I.D. (1997) A Plateau tank apparatus for liquid bridge research. Review of Scientific Instruments 68 (3), 1495-1500.
 
Slobozhanin L., Alexander J.I.D., and Resnick A. (1997) Bifurcation of the equilibrium states of a weightless liquid bridge. Phys. Fluids 9 (7), 1893-1905.
 
Alexander, J. I. D., Delafontaine, S., Resnick A. and Carter, W. C. (1996) Stability of Non-axisymmetric Liquid Bridges. Microgravity Sci. Technol. IX/3, 193-200.

Mailing Address
Center for Gene Regulation in Health and Disease (GRHD)
2121 Euclid Avenue, SR 259
Cleveland, OH 44115

Campus Location
2351 Euclid Avenue
Science and Research Building, Room 259
Phone: (216) 687-2516
Fax: (216) 687-5549
d.jackel@csuohio.edu

GRHD Logo